Comparing two mesh types for breast reconstruction after cancer surgery

This trial is testing whether biological mesh (made from processed animal tissue) or synthetic mesh (made from man-made fabric) works better when used to support a breast implant during immediate reconstruction surgery after mastectomy. Both types of mesh are already used in the NHS, but doctors don't yet know which one leads to better long-term outcomes or how safe each is over time. This feasibility study will help researchers understand whether patients and surgeons feel comfortable participating in a larger comparison study.

Right now, surgeons choose which mesh to use based on their own experience and hospital budget, not on solid evidence. A previous review suggested both meshes may be equally safe in the short-term, but we need long-term safety information and a direct side-by-side comparison. This trial also needs to understand whether patients' personal values—such as religious beliefs or views on animal welfare—affect which mesh type they prefer.