Plain-English translation of NCT05451303 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are evaluating a new test called the OralViome Cancer Testing System that analyzes saliva to detect oral and throat cancers in their early stages. The study compares saliva samples from people with cancer, people with precancerous mouth conditions, and people without cancer to see if the test can reliably identify who has cancer.
Oral and throat cancers are often caught late, when they're harder to treat. This trial exists to develop a simple, noninvasive way to catch these cancers earlier using just a saliva sample, which could help people get treatment sooner.
You likely qualify if…
You likely don't qualify if…
If you have cancer or a precancerous mouth condition, you'll provide a saliva sample and complete health questionnaires, with follow-up visits over up to one year. If you're cancer-free, you'll complete one visit where you give a saliva sample and answer questions about your health. All saliva samples can be collected at home or in a clinic using kits provided by the research team.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States
Collaborators
New York Medical College
Enrollment target
~475 participants
Started
May 2022
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mory Mehrtash, MSc
Viome
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.