Plain-English translation of NCT05455515 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is tracking how well a procedure called intravascular lithotripsy (using the Shockwave catheter) works for patients with severely calcified heart artery blockages. The treatment uses shock waves to break up calcium deposits so doctors can place stents to open the artery. Researchers will follow 2,000 patients across about 30–50 Italian hospitals to see how safe and effective this treatment is over one year.
Some heart artery blockages become very hard and calcified, making them difficult or impossible to treat with standard balloon angioplasty and stent placement. This study exists to understand whether shock wave lithotripsy is a safe and effective solution for these challenging, heavily calcified lesions.
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You will undergo a heart catheterization procedure where doctors use the Shockwave catheter to break up calcium in your blocked artery, then place a stent to keep it open. Before and after the procedure, you may have imaging tests like ultrasound or optical scans. You will be asked to take specific blood thinning medications for at least one year and attend follow-up clinic visits to check your heart health, with a complete evaluation at one year after your procedure.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
Italy