Plain-English translation of NCT05456958 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Post Traumatic Stress Disorder research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial uses a special type of brain imaging called real-time fMRI neurofeedback to help people with PTSD. During the scanning sessions, you'll see live feedback showing how active certain parts of your brain are, and you'll learn techniques to help calm those areas. Researchers believe this real-time feedback might help your brain learn to regulate stress responses related to your trauma.
PTSD can feel overwhelming because certain brain regions stay overactive when you encounter reminders of trauma. This treatment aims to help your brain learn to regulate itself by giving you immediate feedback during brain imaging, which may offer a new way to reduce symptoms beyond traditional talk therapy.
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You will attend baseline clinical interviews where a clinician confirms your PTSD diagnosis and you select trauma-related words for the study. Then you'll have three MRI scanning sessions where you'll see real-time feedback of your brain activity and practice regulation techniques; each session includes a brief interview afterward. Throughout the 7-week study, you'll wear a small device to track your sleep and activity, and complete brief questionnaires online about your symptoms.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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