Adding a cholesterol-lowering injection to statin therapy after heart attack

This trial is testing whether adding a medication called a PCSK9 inhibitor (either Alirocumab or Tafolecimab, depending on timing) to high-dose statin therapy can help prevent future heart attacks and other serious heart events in people who have recently had a heart attack and undergone a procedure to open blocked arteries. The medication works by helping your body remove more cholesterol from your blood. Researchers want to know if this combination therapy is more effective than statin therapy alone at protecting your heart.

Even after a heart attack and treatment to open blocked arteries, many patients still have high cholesterol levels and remain at risk for future heart problems. Current guidelines recommend high-dose statins, but doctors want to know if adding this powerful cholesterol-lowering treatment can provide extra protection and prevent more heart events.