Plain-English translation of NCT05459597 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying how seizure medications—including phenytoin, carbamazepine, lamotrigine, levetiracetam, and parempanel—work in older adults. The goal is to understand how these medications move through the body and how well they work at different doses, so doctors can recommend the best treatment plan for elderly patients with seizures.
As we age, our bodies process medications differently, which means older adults may need different doses than younger people. This study aims to fill that knowledge gap so doctors can prescribe the medication at doses that are both safer and more effective for seniors.
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You would continue taking your seizure medication as prescribed by your doctor. Researchers will review your medical records, monitor how well the medication is working for you, and may ask you to provide blood samples so they can measure medication levels in your body. The study will help doctors understand whether your current dose is right for you.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
China
Qianfoshan Hospital, The Second Hospital of Shandong University
Enrollment target
~500 participants
Started
January 2021
Primary completion
March 2028
Age range
65 Years – 100 Years
Last updated on clinicaltrials.gov in July 2022.
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Central contact
Wei Zhao
Qianfoshan Hospital
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