Plain-English translation of NCT05459636 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a simple daily breathing exercise using a handheld device called inspiratory muscle strength training (IMST). Researchers want to see whether doing these breathing exercises every day for 8 weeks can lower blood pressure, improve how well your lungs work, and make it easier to breathe during physical activity — all without requiring major exercise or weight loss.
Many adults with obesity struggle with shortness of breath during activity, which keeps them from exercising. Since regular exercise can improve heart health and lower blood pressure, researchers want to find a quicker, easier way to get some of those same benefits using just a few minutes of daily breathing exercises.
You would use a handheld breathing device at home every day for 8 weeks. The device creates resistance that makes breathing in more challenging, similar to a workout for your breathing muscles. Half of participants will use a stronger resistance level, and half will use a very gentle resistance (as a comparison). Researchers will measure your blood pressure, test your lung function, and assess how you feel during activity before and after the 8 weeks.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States
Sponsor
Florida State University
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~44 participants
Started
December 2023
Primary completion
September 2026
Age range
18 Years – 45 Years
Last updated on clinicaltrials.gov in October 2026.