A Phase II Randomized, Open Label Non-inferiority Study of NiraParib Maintenance After 3 vs. 6 Cycles of Platinum-based Chemotherapy in completeLy debUlked Advanced HRDpositive High-grade Ovarian Cancer patientS in First Line Therapy — Stella
Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
(47 sites) Austria
Universitätsklinik Innsbruck, Innsbruck Belgium
Cliniques Universitaires St. Luc, Brussels Jessa ziekenhuis, Hasselt Czechia
University Hospital Ostrava, Ostrava General University Hospital in Prague, Prague University Hospital Bulovka, Prague Germany
Universitätsklinikum Aachen, Aachen Klinikum Mittelbaden Baden-Baden Bühl, Baden-Baden DRK-Kliniken Berlin-Köpenick, Berlin Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin ZAHO Bonn Onkologische Praxis, Bonn Universitätsklinikum Carl Gustav Carus, Dresden Florence-Nightingale-Krankenhaus Düsseldorf-Kaiserswerth, Düsseldorf Universitätsklinikum Freiburg, Freiburg im Breisgau Universitätsklinik Göttingen, Göttingen Universitätsklinikum Hamburg-Eppendorf, Hamburg SLK-Kliniken Heilbronn, Heilbronn Italy
Policlinico St. Orsola Malpighi, Bologna ASST Spedali Civili di Brescia, Brescia ASST Lecco - Ospedale A. Manzoni, Lecco IRCCS Istituto nazionale dei Tumori, Milan Istituto Oncologico Veneto (IOV), Padova Azienda Ospedaliera Universitaria Pisana, Pisa Azienda USL IRCCS Di Reggio Emilia, Reggio Emilia AO Ordine Mauriziano, Torino AOU CittĂ della Salute e della Scienza di Torino - Ospedale Sant'Anna, Torino Spain
Hospital General Universitario Dr. Balmis, Alicante Hospital Virgen de las Nieves, Granada Hospital Universitario Lucus Augusti, Lugo CIOCC Clara Campal, Madrid H. Althaia Manresa, Manresa H.U. Virgen de la Macarena, Seville Hospital Universitario Virgen del RocĂo, Seville Hospital Universitario Sant Joan de Reus, Tarragona Hospital General Universitario de Valencia, Valencia
Key details Sponsor
North Eastern German Society of Gynaecological Oncology
Collaborators
Institut fĂĽr Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Enrollment target
~640 participants
Primary completion
October 2032
Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel
Universitätsklinikum Leipzig, Leipzig Universitätsklinik der Johannes-Gutenberg Universität Mainz, Mainz Diakonie Klinikum Schwäbisch Hall, Schwäbisch Hall Christliches Klinikum Unna Mitte, Unna Helios Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden Age range
18 Years and older
Last updated February 2026