Plain-English translation of NCT05463289 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 1 Diabetes research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether an artificial intelligence (AI) system can accurately screen young people with type 1 or type 2 diabetes for diabetic retinopathy—a serious eye condition that can develop when diabetes damages blood vessels in the back of the eye. Researchers want to see if this quick, point-of-care AI eye exam can reach more young people, especially those in underserved communities, and catch eye problems early so they can get the care they need.
Many young people with diabetes don't get regular eye screenings because it's hard to access a specialist or schedule a dilated eye exam. This trial tests whether using AI to screen eyes on the spot—similar to how a blood pressure check works—can make screening easier and faster, especially for youth in minority and underserved communities.
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You will visit a study center where a special camera (called a non-mydriatic fundus camera) will take pictures of the back of your eye—similar to taking a photograph, without needing eye drops or dilation. An AI system will analyze these images right away and give you the results immediately. If the AI detects any signs of eye damage, you'll be referred to an eye care provider for a more detailed dilated eye exam to confirm the findings.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States
Sponsor
Johns Hopkins University
Collaborators
National Eye Institute (NEI), Juvenile Diabetes Research Foundation
Enrollment target
~500 participants
Started
July 2022
Primary completion
September 2026
Age range
8 Years – 21 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Risa M Wolf, MD
Johns Hopkins University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.