Plain-English translation of NCT05466851 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Depression research guide →Researchers want to understand depression and anxiety better by looking at biological markers — things like stress hormones and immune system changes — alongside your symptoms and thinking patterns. This study will collect blood samples, medical information, and cognitive assessments from 200 adults to build a clearer picture of how depression and anxiety work in different people.
Brain scans can show differences in people with depression, but they're expensive and hard to use in regular doctor's offices. This research aims to find simpler, more practical biological markers that doctors could use to diagnose depression and anxiety more accurately and predict which treatments will work best for each person.
You likely qualify if…
You likely don't qualify if…
You would visit the study center for appointments where researchers will collect blood samples, review your medical history, and have you complete questionnaires and cognitive tests to measure thinking and mood. The study team will track your progress as you receive standard clinical treatment (medication and therapy) and monitor subtle changes in your stress response and other biological markers over time. The exact number of visits and duration will be determined during enrollment.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States