Plain-English translation of NCT05469607 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study evaluates the safety of vagal nerve neuromodulation — a technology that gently stimulates a nerve in your body — in people with Crohn's disease who have had surgery to remove diseased bowel. The goal is to see if this treatment can help prevent the disease from coming back after surgery.
After surgery for Crohn's disease, the condition often returns in the remaining bowel, and doctors need new approaches to prevent this. This trial explores whether stimulating the vagus nerve might help reduce inflammation and lower the risk of recurrence.
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As a participant, you would receive the vagal nerve neuromodulation device during your recovery from Crohn's surgery. You would then have follow-up visits where doctors monitor your safety and check how well you're healing using colonoscopy and other standard exams. The study will track whether the treatment is safe and how your disease responds over time.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
Australia
Sponsor
Austin Health
Collaborators
The Florey Institute of Neuroscience and Mental Health, University of Melbourne
Enrollment target
~13 participants
Started
July 2022
Primary completion
December 2026
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in February 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Peter De Cruz, MBBS PhD FRACP
Austin Health, Melbourne
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.