Plain-English translation of NCT05477277 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating how muscle health and composition—specifically muscle volume and fat content—affects outcomes after liver transplant. Researchers will use MRI scans (imaging tests you may already be getting as part of your transplant evaluation) to measure your muscle quality and identify patients at higher risk for complications or poor outcomes after transplant.
Many people with end-stage liver disease lose muscle mass and develop fatty changes in their remaining muscle, which can lead to worse health outcomes and reduced survival after transplant. This study aims to create a simple way to identify which patients are at highest risk, so doctors can potentially intervene earlier and improve transplant results.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will complete an MRI scan of your thigh muscle as part of your routine transplant evaluation—no extra visits needed. Researchers will analyze these images to measure your muscle volume and fat content, then follow your health outcomes after transplant to understand how muscle quality relates to recovery and survival. The study aims to enroll 100 patients total.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Collaborators
Amra Medical AB
Enrollment target
~100 participants
Started
November 2022
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Latasha Bunkley
Mayo Cinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.