Plain-English translation of NCT05477680 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During brain surgery, the brain naturally moves and shifts as the surgeon works — a phenomenon called brain shift. This study aims to measure how much the brain moves during different types of brain surgery and understand patterns that might help predict it. By tracking this movement carefully, researchers hope to help surgeons navigate more accurately and safely during future operations.
Brain shift is one of the biggest reasons why surgical navigation systems lose accuracy during brain surgery. Currently, surgeons have limited reliable ways to measure or predict this movement in real time, which can affect how precisely they can reach and remove brain lesions. This study seeks to gather data that could eventually help improve surgical precision and patient safety.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would undergo brain surgery as planned for your condition, using standard surgical navigation technology. During your operation, the surgical team will carefully document the location of brain structures and the lesion they are treating. After surgery, researchers will compare these intraoperative observations with imaging and patient information collected afterward to understand how your brain shifted during the procedure. Your participation helps build knowledge that may improve surgical precision for future patients.
AI-generated summary from trial data · Jul 6, 2026 · Not medical advice
Russia
Sponsor
Sklifosovsky Institute of Emergency Care
Enrollment target
~100 participants
Started
September 2022
Primary completion
August 2027
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Alexander Dmitriev, MD
Sklifosovsky Institute of Emergency Care
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.