Plain-English translation of NCT05478876 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing carbon ion radiation therapy, a focused form of radiation treatment, for women with melanoma (a type of cancer) in the lower genital tract. Carbon ion radiation is a specialized type of radiation that may be more effective than standard radiation because it targets tumors more precisely. After receiving the radiation treatment, participants will also receive immunotherapy (a type of treatment that helps the body's immune system fight cancer).
Melanoma in the gynecological area is rare and difficult to treat, especially for patients who cannot have surgery or have already received standard radiation therapy. This trial exists to test whether this advanced form of radiation therapy can help control the cancer and improve outcomes for these patients.
You likely qualify if…
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If you qualify, you will first undergo baseline exams, imaging scans (CT and MRI), and a planning session to map out your radiation treatment. You will then receive carbon ion radiation therapy according to the study plan. After completing radiation, you will receive immunotherapy that is not given at the same time as the radiation. Throughout the study, your doctors will monitor how you respond to treatment using imaging and clinical evaluations.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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