Plain-English translation of NCT05485961 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a medication called that reduces inflammation in the body. It's designed for people with end-stage kidney disease who are on dialysis and have heart disease or diabetes. Researchers want to see if this medication can help prevent heart problems and is safe to use in this group of patients.
People on dialysis often have high levels of inflammation in their blood, which can lead to serious heart problems. This medication is being tested to see if reducing that inflammation can help protect their hearts and improve their health.
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The trial has two parts. First, researchers test different doses of the medication to find the safest and most effective one. Then, participants receive either the medication or a placebo (a dummy treatment) as an intravenous infusion on a regular schedule. You will have blood tests and check-ins to monitor your health and any side effects throughout the study, which lasts several months to over a year depending on which part you join.
AI-generated summary from trial data · Oct 4, 2026 · Not medical advice
United States