Plain-English translation of NCT05487053 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different nerve block techniques to manage pain after total knee replacement surgery. One method, called an adductor canal block, is newer and may allow your leg muscles to work better after surgery. The other, called a femoral nerve block, is the current standard but can temporarily weaken your thigh muscles. This study will compare how well each method works for pain relief and how quickly you can move and recover.
More than half of patients have severe pain after knee replacement surgery, which can slow recovery and increase the risk of falling. The standard pain relief method works very well but can temporarily weaken your thigh muscles, making it harder to walk and exercise. This trial is testing whether the newer approach can give you the same pain relief while keeping your leg strength better, so you can recover faster and safer.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will receive one of the two pain relief nerve blocks before or after your knee replacement surgery as part of your standard care. You will be randomly assigned to receive either the single-shot adductor canal block or the continuous femoral nerve block. Your recovery and pain levels will be monitored during your hospital stay and through follow-up visits, where your doctors will track how well you are moving and managing pain.
AI-generated summary from trial data · Aug 1, 2026 · Not medical advice
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