Plain-English translation of NCT05488093 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to better understand how knee replacement surgery affects the way people move and function in their daily lives. Currently, doctors mainly rely on patient questionnaires and pain scales to measure recovery, but these don't fully capture real-world movement patterns like walking, climbing stairs, or getting up from a chair. This study will use special motion sensors and imaging tests to objectively measure how your movement improves after surgery.
Severe knee arthritis can make everyday activities extremely difficult, and knee replacement surgery is the main treatment option at this stage. However, doctors don't have good tools to measure true functional recovery and predict which patients will benefit most from surgery. This research aims to identify better ways to assess movement and predict outcomes so doctors can provide more personalized care.
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You will visit the hospital four times over 12 months. Before surgery, you'll have a baseline visit where doctors will examine your knee, ask you about pain and function, take blood samples, perform imaging scans (MRI and bone density scans), and have you wear special motion sensors while doing simple movements. During surgery, a small muscle sample will be collected. At 12 months after surgery, you'll return for final testing including the same movement tests, imaging, and blood work to measure your recovery. Each visit takes a few hours.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
France