Plain-English translation of NCT05488665 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When a heart artery branches into two vessels and both branches are blocked, doctors need to place two stents to restore blood flow. This trial is comparing two different techniques—called the Crush technique and the Culotte technique—to see which one leads to better results one year after treatment. Both techniques use modern drug-eluting stents, which are stents coated with medication to prevent the artery from closing again.
Bifurcation lesions (blockages at artery branch points) are tricky to treat, and doctors want to know which stent placement technique gives patients the best long-term outcomes with the fewest complications.
You likely qualify if…
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You will undergo a heart catheterization procedure where doctors will place two stents in your blocked artery using either the Crush or Culotte technique (randomly assigned). After the procedure, you will have follow-up appointments over one year to monitor how well your artery stays open and check for any complications. The study team will track your heart health and any symptoms during this period.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
South Korea
Sponsor
Yonsei University
Enrollment target
~512 participants
Started
November 2022
Primary completion
September 2027
Age range
19 Years and older
Last updated on clinicaltrials.gov in October 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Byeong-Keuk Kim, MD, PhD
Division of Cardiology, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.