Plain-English translation of NCT05489211 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new cancer medication called to see if it can help people with advanced or metastatic solid tumors. The study will test this medication both as a standalone treatment and in combination with other approved cancer drugs, depending on your cancer type. Researchers want to understand how well the medication works and how safe it is across seven different cancer types.
Many people with advanced cancers need new treatment options because existing therapies don't always work well enough or cause too many side effects. This trial exists to see whether the medication—alone or paired with other drugs—could offer better results for patients with cancers that have spread.
You likely qualify if…
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Depending on which cancer type you have, you will receive the new medication either by itself or combined with one or more other approved cancer drugs. The study involves multiple visits to the clinic for medical check-ups, blood tests, tumor measurements, and tissue samples. You will need to provide a tumor sample for analysis and may be asked to participate in optional genetic research. The exact schedule and duration will depend on which substudy group you join and how your cancer responds to treatment.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States