Plain-English translation of NCT05490901 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This research study investigates whether performing heart imaging tests while you exercise โ combined with a special heart catheterization procedure โ can more accurately diagnose the cause of your shortness of breath during physical activity. Researchers want to understand how your heart responds to stress and whether this combined approach can identify conditions like heart failure or blood clots in the lungs that are difficult to spot when you're at rest.
Many people experience shortness of breath only when they exercise, but standard heart tests performed while resting don't show any problems. This trial aims to fill that gap by testing whether combining exercise stress imaging with invasive heart monitoring can catch heart and lung conditions earlier and help doctors choose better treatments.
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You will undergo heart imaging tests both while resting and while exercising on a special machine. During the exercise portion, doctors will also perform a heart catheterization โ a minimally invasive procedure where a thin tube is placed in a heart vessel to measure blood flow and pressures directly. The study compares the information from these combined tests to help doctors develop better ways to diagnose exercise-related shortness of breath. Your participation helps researchers understand how your heart responds to stress and may improve diagnosis for future patients with similar symptoms.
AI-generated summary from trial data ยท Jun 5, 2026 ยท Not medical advice
South Korea
Sponsor
Samsung Medical Center
Enrollment target
~400 participants
Started
March 2020
Primary completion
December 2028
Age range
19 Years and older
Last updated on clinicaltrials.gov in August 2022.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Jeong Hoon Yang, MD
Samsung Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.