Plain-English translation of NCT05491005 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Diabetes Mellitus, Type 2 research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether an intensive weight loss program can help people with type 2 diabetes achieve remission—meaning their blood sugar returns to normal levels without needing diabetes medication. You would follow a structured eating plan for 3 months designed to help you lose weight, then gradually return to regular foods while maintaining your weight loss. The study compares two ways of getting support: through an online app with video check-ins, or through regular office visits with a doctor, nurse, and dietitian.
Research shows that significant weight loss can sometimes reverse type 2 diabetes, but many people struggle to lose weight and keep it off on their own. This trial is testing whether a combination of an intensive eating plan and personalized support—delivered either digitally or face-to-face—can help more people successfully achieve and maintain weight loss and diabetes remission.
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You would be randomly assigned to receive follow-up care either through an online app or through in-person office visits. For the first 3 months, you would follow a structured eating plan (about 850 calories per day) with the goal of losing at least 15 kg. You would track your weight, blood sugar, and blood pressure regularly and attend appointments with a dietitian, nurse, or doctor to discuss your progress. After 3 months, you would gradually return to regular foods while learning strategies to maintain your weight loss. The study lasts 2 years total, with ongoing support and check-ins throughout.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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