Plain-English translation of NCT05494502 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Neoplasms research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a procedure called an erector spinae plane block, combined with the medication dexmedetomidine, can prevent chronic pain in people having breast cancer surgery. Chronic pain after breast cancer surgery affects nearly half of patients and can seriously impact quality of life. Researchers believe that controlling acute pain right after surgery — using this nerve block technique — may stop long-term pain from developing in the first place.
Chronic pain lasting months or years after breast cancer surgery is common and affects patients' everyday functioning and mental health. While nerve blocks are known to help with pain immediately after surgery, this trial wants to find out whether this particular technique with the medication can also prevent chronic pain from occurring at all.
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If you qualify, you would be randomly assigned to receive either the nerve block procedure with medication before surgery, or standard anesthesia alone. The nerve block takes about 10–15 minutes and involves an ultrasound-guided injection in your upper back before you go under general anesthesia. After surgery, researchers will follow you over several months to track your pain levels and quality of life using questionnaires and assessments.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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