Plain-English translation of NCT05495776 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →This is a research registry study that enrolls patients newly diagnosed with colorectal cancer. Researchers will collect small blood samples and tumor tissue samples from you to test whether you carry genetic changes that increase cancer risk in your family. This information helps doctors understand who may benefit from different treatment approaches and helps protect your relatives.
Some colorectal cancers are caused by inherited genetic changes that run in families—a condition called Lynch syndrome. This study aims to discover how often this inherited condition occurs in colorectal cancer patients in Russia, and to learn whether identifying these genetic changes helps doctors choose better treatments and prevent cancer in family members.
You likely qualify if…
You likely don't qualify if…
If you qualify, a doctor or nurse will take a small blood sample (about 4 milliliters) and collect a sample of your tumor tissue during your endoscopy or surgery. Your samples will be tested to look for genetic changes related to inherited cancer risk. You will then be followed for 5 years through your regular medical care, during which researchers will track how your cancer responds to treatment and gather family health information to better understand inherited cancer patterns.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Russia
Sponsor
State Scientific Centre of Coloproctology, Russian Federation
Collaborators
The Loginov MCSC MHD, Pirogov National Medical and Surgical Center
Enrollment target
~2,500 participants
Started
August 2022
Primary completion
August 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in October 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Dmitrii Semenov, PhD
Head of the Department of Laboratory Genetics
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.