Plain-English translation of NCT05497180 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Sleep apnea causes your airway to collapse while you sleep, interrupting your breathing. This trial is testing whether a newer type of dental device called a passive myofunctional appliance—which gently positions your tongue, cheeks, and lips to keep your airway open—works as well as or better than the traditional jaw-forward dental device that has been used for years. The research team wants to know if the newer device might be more comfortable and cause fewer jaw or face problems.
The traditional jaw-forward dental device can sometimes cause jaw pain or joint problems because it pushes your lower jaw forward significantly. Recent research suggests that newer approaches using gentler muscle-positioning techniques might work just as well without these uncomfortable side effects, but this hasn't been thoroughly tested yet.
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You will be randomly assigned to receive either the newer passive myofunctional appliance or the traditional jaw-forward dental device. You'll wear your assigned device as instructed and attend follow-up visits so the research team can measure how well it's working and check for any side effects. The study will track how well you sleep, whether your snoring improves, and how comfortable the device feels during daily use.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
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