Plain-English translation of NCT05501743 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new treatment called autologous microfat combined with platelet-enriched plasma—a special injection made from your own body's healing cells—to see if it can reduce wrist arthritis pain as effectively as a surgical nerve procedure. You have severe wrist arthritis that hasn't improved with standard treatments like pain relievers, anti-inflammatory medications, or other injections. The study will compare how well this new injection works compared to the established surgical treatment over 6 months.
Wrist arthritis can cause severe pain and limit your ability to use your hand in daily life, and current treatment options are limited. Researchers want to know whether this injection treatment—which uses your body's own cells to reduce pain—might work as well as surgery, while potentially being simpler and safer.
If you are assigned to receive the new injection treatment, you will visit the hospital for a half-day outpatient procedure lasting about 4 hours. Your own fat cells will be harvested and combined with your blood platelets in the operating room, then injected into your wrist joint. You will be followed up with visits and assessments at 1 week, 3 months, 6 months, and 12 months to track your pain relief and how well you can use your wrist. Some visits will include imaging (MRI scans) to check how your wrist cartilage is healing.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
France