Plain-English translation of NCT05503875 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Psoriasis affects everyone differently, and not all treatments work equally well for all patients. This trial is testing whether studying your individual immune system cells can help doctors predict which medication—such as adalimumab, secukinumab, ixekizumab, guselkumab, JAK inhibitors, or methotrexate—will work best for you. The researchers use advanced laboratory techniques to understand exactly how your immune system responds to treatment.
Many people with psoriasis don't respond well to standard treatments, and doctors currently have limited tools to predict which medication will help each patient. This study aims to solve that problem by creating a personalized approach—using detailed information about your immune cells to guide treatment decisions and help more patients find relief.
You likely qualify if…
You likely don't qualify if…
You will receive one of several standard psoriasis medications as part of routine care. At the same time, researchers will take blood or skin samples to study your immune system cells in detail using advanced laboratory methods. This helps them understand why certain treatments work better for some patients than others. The study will track your response to treatment over time to build a better system for matching patients with their most effective medication.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
China
Sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine
Enrollment target
~100 participants
Started
January 2023
Primary completion
December 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in January 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Xiao-yong Man
Second Affiliated Hospital, Zhejiang University, School of Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.