Plain-English translation of NCT05505357 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether some breast cancer patients can safely skip surgery after chemotherapy if special imaging (MRI) and a tissue biopsy show that the cancer has completely disappeared. Researchers want to confirm that patients who meet very strict criteria—showing no cancer cells on biopsy and specific MRI findings—have the same survival outcomes whether or not they have surgery. This could spare patients from an operation and its recovery if it's truly not needed.
After chemotherapy, some patients have no remaining cancer in their breast, but they still undergo surgery as standard care. This trial exists to see whether surgery can be safely skipped for these patients, which would reduce unnecessary procedures, recovery time, and medical costs while maintaining excellent health outcomes.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo an MRI scan and a needle biopsy (vacuum-assisted biopsy) of the tumor area to confirm there are no remaining cancer cells. If the biopsy shows complete response, you will skip breast surgery but may have a sentinel lymph node biopsy depending on your specific cancer characteristics. You will then be followed over time to monitor your health and ensure you remain cancer-free, with regular check-ups and imaging as part of standard care.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
South Korea