Plain-English translation of NCT05514288 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing endoscopic bariatric therapy (EBT)—a minimally invasive procedure performed through the mouth and throat that reshapes your stomach to help you feel fuller faster and lose weight. You'll also receive support through diet counseling, exercise guidance, and behavior coaching. The study will track your weight loss, measure changes in hormones related to appetite and metabolism, and assess how the treatment affects your quality of life over one year.
Many people struggle to lose weight or keep it off, even after trying diet and exercise alone. This treatment offers a less invasive option than traditional weight loss surgery, which may help people achieve significant weight loss while reducing risks associated with major surgery.
You likely qualify if…
You likely don't qualify if…
You will undergo one of two minimally invasive endoscopic procedures—either endoscopic sleeve gastroplasty or transoral outlet reduction—performed by a specialist. After the procedure, you'll participate in a behavioral program that includes meeting with a dietitian for meal planning, working with an exercise specialist, and receiving behavior coaching to help you make lasting lifestyle changes. You'll have regular follow-up visits over one year where the team will measure your weight, take blood samples to check hormone levels, and assess how you're doing.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
United States
Sponsor
Cedars-Sinai Medical Center
Enrollment target
~20 participants
Started
November 2022
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Liliana Bancila, PhD
Cedars-Sinai Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.