Plain-English translation of NCT05518305 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →After a stroke or mini-stroke caused by narrowed brain arteries, many people have another stroke even while taking blood-thinning medications. This study is looking at two things that might predict who will have a repeat stroke: a specific marker on blood cells (called FcγRIIa) and the patterns of blood flow through the narrowed arteries. By understanding these markers better, doctors hope to personalize treatment to prevent future strokes.
Despite using blood-thinning medications, strokes caused by narrowed brain arteries keep happening. Researchers believe that individual differences in how blood flows through these narrowed areas and how a person's blood cells respond might explain why some people have repeat strokes while others don't—and this knowledge could help doctors prevent strokes more effectively.
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At your first visit, you will have a blood sample taken and a brain MRI scan, along with a standard thinking and memory test. You will return for a check-in visit at 3 months to make sure you have had no problems. At 12 months, you will have another brain MRI and thinking test. The entire study lasts about 1 year, and you will be followed carefully to watch for any side effects or additional strokes.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
United States
Sponsor
University of California, Los Angeles
Collaborators
University of Pittsburgh Medical Center, University of Chicago
Enrollment target
~250 participants
Started
September 2022
Primary completion
September 2027
Age range
30 Years and older
Last updated on clinicaltrials.gov in June 2026.
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Central contact
David Liebeskind, MD
University of California, Los Angeles
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