Plain-English translation of NCT05519046 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study compares two types of implanted devices designed to help your heart pump more effectively if you have heart failure from Chagas disease. One device (Cardiac Contractility Modulation) sends electrical signals to strengthen your heart's contractions, while the other (Cardiac Resynchronization Therapy) coordinates the timing of your heart's chambers. Researchers want to see which approach works better for people with this specific type of heart disease.
Heart failure from Chagas disease is a serious condition that affects millions of people, especially in Latin America, and current treatment options are limited. This trial explores whether these specialized heart devices can reduce symptoms, improve quality of life, and help people live longer when they have this condition.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would be randomly assigned to receive one of the two heart devices through surgical implantation. The study will then monitor your heart function, symptoms, and overall quality of life over time to see how well the device works for you. You would have follow-up visits to check on your device, run tests to measure your heart's performance, and report how you're feeling.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
Brazil