Testing a hormone-blocking medication to prevent bladder cancer recurrence

This study is testing whether bicalutamide, a medication that blocks male hormones, can help prevent bladder cancer from returning after surgery. Researchers believe that hormones may play a role in how bladder cancer grows back, so this medication might reduce that risk. Half of participants will take the medication for three weeks before their bladder cancer surgery, and half will have surgery without the medication first.

Bladder cancer often comes back after treatment, and doctors are looking for ways to prevent recurrence. Early research suggests that male hormones may fuel the growth of bladder cancer cells, so blocking those hormones before surgery might help keep the cancer from returning.