Plain-English translation of NCT05523245 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are building an artificial intelligence tool that analyzes special MRI scan images to predict whether patients with locally advanced rectal cancer will respond well to chemotherapy and radiation therapy given before surgery. This study aims to help doctors know in advance which patients will have the best outcomes, so they can make better treatment decisions.
Currently, doctors cannot reliably predict ahead of time which rectal cancer patients will respond well to pre-surgery treatment. By developing this AI prediction tool, researchers hope to help doctors identify which patients are most likely to benefit and guide treatment planning more accurately.
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You would undergo MRI scans (special imaging tests) as part of your regular cancer evaluation. Researchers will analyze these images using their new AI tool to see how well it predicts whether your cancer responds to your pre-surgery chemotherapy and radiation. Your medical records will be followed to track your treatment response and surgical outcomes, with a time window of about 2 weeks between your final MRI scan and surgery.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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