Plain-English translation of NCT05524324 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial studied cardiac resynchronization therapy (CRT)—a special type of heart pacemaker—in adults born with a condition called systemic right ventricle, where the heart's pumping chambers are reversed. Researchers tested whether turning this pacemaker on and off over 6 months could improve heart function and quality of life in patients with heart failure. Each participant experienced both the pacemaker turned on and turned off during the study to see which setting helped them most.
Adults with congenital heart disease and a weakened right ventricle often struggle with heart failure, but doctors didn't know whether this specialized pacemaker could actually help them. This trial was designed to find out whether the treatment could improve their heart function and daily activities, or whether it might be unnecessary and could cause harm.
Participants received temporary adjustments to their implanted pacemaker over a 6-month period. Half the group started with the pacemaker turned on, then switched to off; the other half started with it off, then switched on. During this time, researchers monitored participants' heart function and symptoms through regular check-ups to compare how they felt and how their hearts performed under each setting.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
France