Plain-English translation of NCT05524324 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing cardiac resynchronization therapy (CRT) — a special pacing function in implanted heart devices — in adults born with congenital heart disease who have a specific type of heart weakness. Researchers want to know whether turning this pacing function on actually improves how you feel, how much you can do, and your quality of life. Right now, doctors aren't sure if this treatment works well for your type of heart condition.
Adults with your type of congenital heart disease often develop heart failure, but it's unclear whether the pacing treatment already helps you or not. This trial exists to answer that question so doctors can make better decisions about whether to use this treatment in the future, and to avoid implanting devices that won't actually help.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to start with your device pacing either turned on or turned off for 3 months, then switch to the opposite setting for another 3 months. Neither you nor your doctors will know which mode you're in at any given time (this is called 'blinded'). Throughout the 6-month study, you'll have regular visits where doctors will check how you're feeling, measure your exercise ability, and evaluate your heart function to see which setting works better for you.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
France