Plain-English translation of NCT05529459 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When you have blockages in your heart arteries, doctors need to decide which ones to treat with stents. This trial compares two different ways of making that decision: one method looks at the anatomy (shape and size) of the blockages, while the other uses a special wire to measure blood flow. Both groups receive drug-eluting stents, which are coated stents that help prevent the artery from closing again.
Doctors don't always agree on which heart blockages need treatment. Some blockages look significant but don't actually restrict blood flow enough to cause problems, while others might look less severe but do affect blood flow. This trial is trying to figure out which decision method leads to better outcomes for patients.
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You will be randomly assigned to one of two groups. Both groups will undergo heart catheterization and receive stents for their blockages, but the way doctors decide which blockages to treat will differ between groups. After your procedure, you'll have follow-up visits at 1 month, 6 months, 12 months, and then yearly for up to 5 years to monitor your heart health and see how well the treatment worked.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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