Plain-English translation of NCT05530512 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing electroacupuncture—a form of acupuncture combined with mild electrical stimulation—as a way to help control high blood pressure. Researchers believe that this treatment may work by calming an overactive nervous system and reducing inflammation in the body, addressing problems that standard blood pressure medications alone may not fully fix. The study will compare four different approaches: two versions focused on specific aspects of nervous system control, a combination of both, and a sham (fake) acupuncture control group.
Although most Americans with high blood pressure take medication, only about half achieve good blood pressure control—and the problem worsens as people age. Researchers believe the root cause involves an imbalance in the nervous system and chronic inflammation that current medications don't fully address. This trial tests whether electroacupuncture can target these underlying causes to improve blood pressure control beyond what medications alone can achieve.
You likely qualify if…
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If you join this study, you will receive electroacupuncture treatment at specific points on your body over a series of visits. You'll be randomly assigned to receive one of four treatments: anti-inflammatory acupuncture, nervous system-calming acupuncture, a combination of both, or sham acupuncture (a control group). Throughout the study, researchers will monitor your blood pressure, measure inflammation markers, and assess how well your blood vessels are functioning to see if the treatment helps improve your condition.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States
Sponsor
University of California, Irvine
Collaborators
National Center for Complementary and Integrative Health (NCCIH)
Enrollment target
~72 participants
Started
January 2023
Primary completion
March 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
45 Years – 75 Years
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ashwini Erande
University of California, Irvine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.