Plain-English translation of NCT05534009 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how well your body's immune system protects you from COVID-19 after vaccination or natural infection. This study will follow healthcare workers from 9 hospitals across 8 countries, collecting small blood samples every 4 months for 12 to 24 months. The goal is to learn how immunity changes over time and how well it works against different variants of the virus.
We know that immunity after vaccination or COVID-19 infection fades over time, and different virus variants may escape protection. By studying healthcare workers across different countries where they received different vaccines and have different infection histories, researchers can better understand these patterns and help inform future vaccination strategies.
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If you join, you'll be asked to donate a small blood sample at enrollment and then every 4 months for the next 1 to 2 years. Your samples will be sent to a central laboratory where researchers will test them to understand your immune response to COVID-19. You'll also need to share information about your vaccination history and any COVID-19 infections you've had.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
Germany
Italy
Lithuania
Mexico