Plain-English translation of NCT05534243 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is looking at patients in emergency departments who need breathing machines and receive paralytic medications (which temporarily prevent movement to help with the breathing tube). Researchers want to see if using succinylcholine, a shorter-acting paralytic, instead of rocuronium (a longer-acting one) can reduce a serious complication called awareness with paralysis — where patients are conscious but cannot move or speak. The study will compare what happens before and after hospitals are taught about this medication choice.
Some patients on emergency breathing machines experience a frightening condition where they become aware and alert but cannot move or communicate because of the paralytic medication. Research suggests that the longer-acting paralytic medication (rocuronium) may be linked to this problem more often than shorter-acting options, so this study aims to teach emergency doctors about safer medication choices and measure whether education helps reduce this traumatic complication.
You likely qualify if…
You likely don't qualify if…
You would not need to do anything special — researchers will follow your medical care as it normally happens in the emergency department. Half the time, your hospital will use standard care practices; the other half, after staff receive education about paralytic medications, your hospital will emphasize the shorter-acting medication. Researchers will review your medical records and track whether you experience awareness while paralyzed and any signs of post-traumatic stress afterward.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States