Plain-English translation of NCT05536076 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new breathing exercise method called intermittent hypercapnia treatment for people with spinal cord injuries who have trouble breathing or sleep apnea. The treatment involves breathing exercises done five days a week for two weeks. Researchers believe this method may help the body restore natural breathing function by stimulating the brain's ability to repair and rewire breathing pathways that were damaged by spinal cord injury.
Spinal cord injuries often damage the nerves that control the diaphragm, the main breathing muscle, leading to severe breathing problems and even the need for a ventilator. Currently, there are no good treatment options beyond machines or nerve stimulators. This study is testing whether this breathing exercise approach could offer a new way to help the body naturally recover breathing strength.
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If you join this study, you will come in five days per week for two weeks to do the breathing exercise treatment. The study team will guide you through breathing exercises that gradually increase carbon dioxide levels in your blood in a controlled, safe way. They will monitor your breathing, heart rate, and how you tolerate the exercises, and may ask you questions about your breathing, sleep, and overall health during and after the treatment.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States