Plain-English translation of NCT05536089 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is testing whether a special blood test—one that looks for tiny traces of tumor material called ctDNA—can help doctors predict if colorectal cancer will return after surgery. Researchers will follow about 2,000 people with early-stage colorectal cancer for up to 5 years, taking blood samples at regular intervals to see if this test is reliable and helpful for monitoring patients and checking whether chemotherapy is working.
Today, doctors struggle to know which patients are at highest risk of cancer coming back after surgery, and it's hard to tell early if chemotherapy is actually working. This blood test could give doctors a faster, easier way to catch a relapse before symptoms appear and adjust treatment plans accordingly.
You likely qualify if…
You likely don't qualify if…
You will have your cancer surgically removed as planned, then return for blood draws at week 3 after surgery, and then regularly over 5 years (every 3 months for the first 2 years, then every 6 months for the remaining 3 years). Your doctors will also check your health and follow your standard cancer care according to national guidelines. The study is watching whether the blood test results match whether your cancer comes back or stays away.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
China
Sponsor
Singlera Genomics Inc.
Collaborators
Second Affiliated Hospital, Zhejiang University, School of Medicine
Enrollment target
~2,000 participants
Started
September 2022
Primary completion
September 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2024.
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Central contact
HongFeng cao, Ph.D
Second Affiliated Hospital, Zhejiang University, School of Medicine
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