Plain-English translation of NCT05541887 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether muscadine wine polyphenols — natural compounds found in muscadine grapes — can help improve your memory, thinking ability, and mood. Researchers believe these compounds may reduce inflammation and oxidative stress in the brain, which could help protect against cognitive decline and anxiety. This is the first study to examine how this specific treatment affects brain health and mental wellbeing.
Scientists have found that similar polyphenol-rich foods like blueberries and grape juice may help with memory and mood, but no one has studied muscadine wine polyphenols yet. This trial aims to fill that gap and understand whether this treatment could be a natural way to support brain health and mental health as you age.
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You will take part in a 12-week study with two 6-week phases separated by a 3-week break. Half of participants will receive the muscadine wine extract first, then switch to a placebo (inactive pill), while the other half will do the opposite. During the study, you will complete memory and thinking tests, and answer questions about your mood and anxiety. The researchers will monitor how you respond to the treatment and compare your results before, during, and after taking the medication.
AI-generated summary from trial data · Jul 14, 2026 · Not medical advice
United States