Plain-English translation of NCT05542407 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether two medications — and — work safely together to treat endometrial cancer that has spread to other parts of the body or has returned after treatment. The study will enroll 58 women and will examine how the treatment works in both obese and non-obese patients, since obesity appears to make this cancer more aggressive.
Endometrial cancer is becoming more common, especially in obese women, and current treatments like chemotherapy often stop working for advanced cases. Doctors need new treatment options, and this trial aims to find out if combining these two medications might help patients whose cancer has spread or come back.
You likely qualify if…
You likely don't qualify if…
You would receive the two medications by injection, with doses adjusted based on your body weight. The trial is in its early phase, focusing on safety, so you would have regular visits for blood tests, imaging scans, and check-ins with the research team to monitor how you respond and watch for any side effects. The exact schedule of visits and length of treatment would be discussed with the study team at enrollment.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States