Plain-English translation of NCT05549102 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how cognitive behavioral therapy—a well-established talk therapy for anxiety—actually changes the way your brain works. This study will use brain imaging and computer-based tasks to see how the brain circuits involved in anxiety respond to treatment, and to figure out why some people respond better than others.
Many people struggle with anxiety, but we don't fully understand how talk therapy helps at the brain level. By studying brain changes during this treatment, researchers hope to predict who will benefit most and eventually improve anxiety care for everyone.
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You will visit a university research center for testing sessions where you'll complete computerized tasks on a computer and undergo an MRI brain scan while performing emotional tasks. Some participants will start cognitive behavioral therapy right away, while others will be on a waiting list during the study period. The research team will measure your brain activity and emotional responses before and after therapy to see how the treatment affects your brain circuits.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
United Kingdom