Plain-English translation of NCT05558111 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is investigating how the brain controls urination in patients who have had orthotopic sigmoid neobladder surgery — a procedure that creates a new bladder from part of the colon after bladder removal. Researchers will use special brain imaging called functional MRI to see which areas of your brain are active when you feel the urge to urinate and when you intentionally control urination. This imaging will help doctors better understand how the brain adapts after this type of surgery.
After neobladder surgery, patients must learn new ways to control urination, but doctors don't fully understand how the brain manages this process. This study aims to fill that knowledge gap so that future treatments and rehabilitation can be more effective.
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You will visit the research center for a brain imaging session using functional MRI. During the scan, you will be asked to perform simple urination-related tasks — such as imagining the urge to urinate or practicing voluntary control — while researchers record your brain activity. The entire visit will take a few hours, and you'll be lying still inside the MRI scanner while these images are taken. The scan itself is painless, though it can be loud and requires you to remain very still.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
China
Sponsor
Zhujiang Hospital
Enrollment target
~40 participants
Started
June 2022
Primary completion
January 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2024.
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Central contact
Chunxiao Liu
Southern Medical University, China
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.