Plain-English translation of NCT05558527 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study explores how social connection—specifically, holding hands with someone—can help regulate your body's stress response and anxiety. Researchers want to understand whether support from a romantic partner, a stranger, or no support at all makes a difference in how your brain and body respond to threatening situations, especially if you've experienced trauma or discrimination in the past.
Trauma and discrimination can leave people feeling constantly on alert and anxious (a condition called hypervigilance). Scientists know that social support helps people manage emotions, but they don't fully understand how this works or whether it's equally helpful for people with trauma histories. This study aims to fill that gap.
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You will visit the research lab and participate in tasks designed to measure how your body reacts to stress. During these tasks, you'll be randomly assigned to one of three conditions: holding your romantic partner's hand, holding a stranger's hand, or holding a stress ball. Researchers will measure your stress responses and vigilance (how alert you are) while you're in each condition to see whether social support makes a difference.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States
Sponsor
University of Nevada, Reno
Enrollment target
~45 participants
Started
December 2025
Primary completion
December 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kylie Baer, MS
University of Nevada, Reno
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.