Plain-English translation of NCT05566483 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a supervised 12-week exercise program can help people recover from long COVID. The program uses gentle, seated exercise like rowing or stationary cycling. Researchers want to see if this training improves heart and lung function, reduces brain fog and fatigue, and helps people feel better overall.
Many long COVID symptoms—like fatigue, brain fog, shortness of breath, and heart racing—may be caused by the heart and lungs becoming deconditioned after weeks of illness and rest. This trial exists to test whether rebuilding your cardiovascular fitness through exercise can reverse these symptoms.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to either start the 12-week exercise program right away or to continue with your usual care (which may become the control group). The exercise program involves supervised sessions using recumbent (seated or slightly reclined) rowing or cycling equipment. You'll have assessments at the beginning and end of 12 weeks to measure your heart function, exercise capacity, symptoms, and quality of life.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
University of Colorado, Denver
Enrollment target
~30 participants
Started
March 2023
Primary completion
October 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
William K Cornwell, III, MD
University of Colorado, Denver
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.