Plain-English translation of NCT05571735 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing how well COVID-19 vaccines work in people who have tuberculosis (TB). Researchers want to understand whether people with TB develop the same protective immune response after vaccination as healthy people do. The study will compare the body's immune response in both groups using blood tests after vaccination.
People with tuberculosis are at higher risk for severe COVID-19 illness, so it's important to know whether this treatment protects them as effectively as it does healthier people. Understanding how well the vaccine works in this vulnerable group will help doctors better protect patients with TB.
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If you join this study, you will receive one of three COVID-19 vaccines (Pfizer-BioNTech, AstraZeneca, or Janssen, depending on what's available). You will then return for blood tests and follow-up visits over 4 to 8 weeks to measure how well your immune system responded to the vaccine. The study team will ask you to report any side effects you experience after vaccination.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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