Plain-English translation of NCT05577585 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether ketamine, an anesthetic medication, can help treat obsessive-compulsive disorder (OCD) more effectively than current treatments. Researchers will give participants one infusion of ketamine and compare it to another medication to see which works better at reducing OCD symptoms. The study will also measure how the medication affects your ability to handle stress and think clearly.
Current treatments for OCD don't work well enough for everyone, and some people don't respond to standard medications or therapy at all. This research aims to explore whether this medication might offer a faster or more effective option for people struggling with OCD symptoms.
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You will receive two infusions: one of the test medication and one of a comparison medication, given about 40 minutes each through an IV. Between or around these infusions, you'll complete some thinking and memory tasks and a cold water stress test while researchers measure your brain activity with EEG. If you choose, you can continue with up to 8 more infusions of the test medication over one month, compared to your regular OCD treatment. The entire study lasts several weeks and involves visits at the medical center.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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