Plain-English translation of NCT05578235 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Crohn Disease research guide โThis study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
When Crohn's disease damages the bowel severely, surgery to remove the diseased section is sometimes necessary. After removal, surgeons must reconnect the healthy bowel โ and there are different ways to do this. This trial compares two surgical techniques: one using hand-stitches and one using surgical staples, to see which approach leads to better outcomes and fewer disease recurrences.
Even with the best surgery and medicines, Crohn's disease often comes back after bowel resection. Researchers believe the surgical technique used to reconnect the bowel may play a role in whether disease recurs, so this trial is testing whether one method is better than the other.
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If you join this trial, you will undergo ileocolic resection (bowel removal surgery), and your surgeon will randomly assign you to receive one of two surgical reconnection techniques โ either hand-stitched or stapled. After surgery, you will return for follow-up visits at 3, 6, and 12 months, during which you'll have imaging scans and a colonoscopy to check how well the surgical site is healing and whether disease has recurred. The study compares how the two techniques affect recurrence rates, bowel function, and overall recovery.
AI-generated summary from trial data ยท Jun 2, 2026 ยท Not medical advice
Netherlands