Plain-English translation of NCT05586282 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at blood proteins in patients who are in the ICU with severe circulation failure — a condition where the heart or body's response to infection causes blood vessels to leak dangerously. The researchers want to understand which proteins in your blood are linked to how much fluid leaks out of blood vessels, which could help doctors predict who is at highest risk and develop better treatments in the future.
Right now, doctors don't fully understand why blood vessels leak so much during severe circulation failure, or how to predict which patients will have the worst leaking. This study exists to identify protein markers that could help answer these questions and eventually lead to better ways to protect patients during these life-threatening emergencies.
You likely qualify if…
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If you are eligible, the research team will ask you or your legal representative for consent to participate. Blood samples will be taken from you as part of your standard ICU care, and the researchers will analyze these samples to measure different proteins. You will not need to do anything special — the samples are collected during routine blood work that is already part of treating your condition in the ICU. The study does not test a new medication or require additional procedures beyond what you are already receiving.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
France
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment target
~380 participants
Started
March 2023
Primary completion
March 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in October 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nicolas BRECHOT, MD, PhD
Assistance Publique - Hôpitaux de Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.