Plain-English translation of NCT05588154 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are building a library of healthy biological samples—including blood, bone marrow, skin, saliva, and stool—to better understand myelodysplastic syndromes, a serious blood disorder that affects how the body makes healthy blood cells. By comparing samples from healthy volunteers with those from patients with the disease, scientists hope to discover new ways to treat this condition and improve outcomes for people living with it.
Myelodysplastic syndromes are difficult to treat and can progress to leukemia, especially in older adults who cannot have a stem cell transplant. Researchers need healthy comparison samples to understand what goes wrong in the disease and develop better treatment options.
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If you enroll, you will be asked to donate one or more types of biological samples at the NIH Clinical Center. Most participants will provide blood and possibly bone marrow; others may provide additional samples such as skin, saliva, or stool. The study is designed to collect samples from 1,000 healthy volunteers over many years, so you may be asked to donate once or at multiple visits depending on the study's needs.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
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