Plain-English translation of NCT05588154 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are collecting samples—blood, bone marrow, skin, saliva, and stool—from healthy volunteers to create a reference database. These healthy samples will help scientists understand what goes wrong in myelodysplastic syndromes, a serious blood disorder where the bone marrow doesn't make enough healthy blood cells. By comparing healthy samples to samples from people with the disease, researchers hope to develop better treatments.
Myelodysplastic syndromes are difficult to treat and often affect older people who cannot have stem cell transplants. Researchers need healthy samples to understand the disease's biology and discover new, more effective treatments.
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You would visit the NIH Clinical Center to donate samples. Depending on which group you join, you might provide blood, bone marrow, skin biopsies, saliva, or stool samples. The study is collecting samples from up to 1,000 healthy volunteers over many years, so your participation involves a one-time visit or a small number of visits to provide your samples.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
United States
Enrollment target
~1,000 participants
Started
January 2023
Primary completion
December 2052
Age range
18 Years – 120 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Danielle F Pinkiert, R.N.
National Cancer Institute (NCI)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.